Which of the following is a side effect of Duloxetine (Cymbalta)?

Duloxetine, marketed as Cymbalta, is a medication primarily used to treat major depressive disorder and generalized anxiety disorder, as well as chronic pain conditions like fibromyalgia. One of the more common side effects of Duloxetine is nausea. This side effect occurs due to the medication's mechanism of action, which increases serotonin and norepinephrine levels in the brain. The gastrointestinal system can be sensitive to changes in neurotransmitter levels, leading to sensations of nausea.

Weight gain can occur with some medications, but it is not a predominant side effect of Duloxetine in the way that nausea is. Similarly, hyperglycemia, or high blood sugar, is not typically associated with Duloxetine as a common side effect. Drowsiness can occur, but it is less common compared to the incidence of nausea in patients taking this medication.

Understanding these side effects helps in managing patient expectations regarding their treatment and contributes to better medication compliance and overall patient well-being.