Which of the following does NOT typically indicate a need for SSRIs?

Bipolar disorder generally does not indicate a need for selective serotonin reuptake inhibitors (SSRIs) as a first-line treatment. SSRIs can sometimes exacerbate manic episodes in individuals with bipolar disorder if not properly managed with mood stabilizers. While SSRIs can be useful for the depressive episodes in bipolar disorder, they are not typically the go-to treatment without the simultaneous use of a mood stabilizer to prevent triggering mania.

In contrast, treatments for obsessive-compulsive disorder, depression, and panic disorder commonly include SSRIs, as these conditions are often linked with serotonin deficiencies. SSRIs are effective in increasing serotonin levels in the brain, which helps alleviate symptoms associated with these disorders.