Which manifestation is typical of opioid abuse?

Severe euphoria is a typical manifestation of opioid abuse because opioids work by binding to specific receptors in the brain, leading to a significant release of dopamine, which is a neurotransmitter associated with feelings of pleasure and reward. This euphoric effect can lead to repeated use as individuals seek to recreate that intense feeling.

In contrast, hyperactivity is generally associated with stimulants rather than opioids, which tend to have a sedative effect. Increased muscle coordination is not a characteristic of opioid use, as opioids can impair motor skills and coordination. Visual hallucinations are more commonly related to hallucinogens or certain mental health disorders, rather than the effects of opioids. Thus, severe euphoria stands out as a hallmark of opioid abuse, making it the correct answer.