Which combination with valerian is noted to result in a greater reduction in symptoms?

The combination of valerian with St. John's Wort is recognized for providing a greater reduction in symptoms, particularly those related to anxiety and sleep disorders. St. John's Wort is known for its antidepressant properties, and when paired with valerian, which is often used for its sedative effects, they can enhance each other's benefits. This can lead to more effective management of mood and anxiety symptoms.

Combining these two herbal remedies can create a synergistic effect, leading to improved overall mental health outcomes compared to using either one alone. In contrast, other combinations may not have the same level of research or established effectiveness when paired with valerian.