What potential risk is associated with large doses of ginkgo biloba?

Large doses of ginkgo biloba are known to be associated with gastrointestinal side effects, including nausea and vomiting. This adverse reaction occurs because ginkgo biloba can stimulate the digestive system, which may lead to discomfort and the expulsion of stomach contents. When individuals consume ginkgo biloba in large quantities, the concentration of active compounds can lead to these unpleasant gastrointestinal symptoms, making nausea and vomiting a potential risk.

While dehydration, severe headaches, and skin rashes can be consequences of various medications or supplements, they are not specifically linked to large doses of ginkgo biloba to the same extent as gastrointestinal issues. This clear association helps identify nausea and vomiting as the primary concern when evaluating the risks of excessive ginkgo biloba intake.