What is the primary indication for the use of SSRIs?

The primary indication for the use of selective serotonin reuptake inhibitors (SSRIs) is major depressive disorder, but they are also commonly prescribed for various anxiety disorders, including generalized anxiety disorder. SSRIs work by increasing the levels of serotonin in the brain, which is often linked to mood regulation and feelings of well-being.

In the context of generalized anxiety disorder (GAD), SSRIs help alleviate the persistent and excessive worry that characterizes this condition. Clinical evidence supports the efficacy of SSRIs in reducing the symptoms of GAD, making them a first-line treatment option.

While SSRIs are also effective for panic disorder, post-traumatic stress disorder (PTSD), and obsessive-compulsive disorder (OCD), the question asks for the primary indication. Generalized anxiety disorder stands out due to its prevalence and the common practice of prescribing SSRIs specifically for that condition. This is aligned with their role in treating chronic anxiety symptoms rather than episodic conditions, which can be more effectively managed with other therapeutic approaches or medications.