What cardiovascular issue may occur as a side effect of Venlafaxine?

Venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI), can lead to hypertension as a notable side effect, especially at higher doses. This is primarily due to its mechanism of action, which increases norepinephrine levels in the brain, leading to potential increases in blood pressure. Clinically, this means that when the medication is administered, patients may experience a rise in blood pressure that requires monitoring, particularly if they have pre-existing hypertension or cardiovascular conditions.

The development of hypertension as a side effect is significant enough that healthcare providers often recommend regular blood pressure check-ups for patients on this medication. Many patients may not realize the potential cardiovascular implications of Venlafaxine, thus making awareness and screening important components of patient care when prescribing this drug.