What are the side effects of SAMe?

SAMe, or S-adenosylmethionine, is a compound that naturally occurs in the body and is often used as a dietary supplement for various health conditions, particularly depression and osteoarthritis. When assessing the side effects associated with SAMe, it is important to recognize that gastrointestinal disturbances are among the most common reactions.

The specific side effects of nausea, vomiting, and diarrhea are linked to the way SAMe can affect the gastrointestinal tract. These symptoms often arise from its potential to increase the levels of certain neurotransmitters, leading to changes in digestive function. As a result, these gastrointestinal side effects are frequently reported by users of the supplement, making this choice the most accurate representation of the potential adverse reactions related to SAMe supplementation.

Other side effects mentioned in the alternative options, such as chest pain and sweating, or fatigue and lethargy, are less commonly associated with the use of SAMe and indicate different underlying issues or reactions not typically linked to this supplement. Therefore, the presence of nausea, vomiting, and diarrhea is the most characteristic side effect profile for SAMe.