Should benzodiazepines be avoided in treating panic disorder for patients with a history of substance abuse?

Benzodiazepines should generally be avoided in treating panic disorder for patients with a history of substance abuse due to their potential for dependence and abuse. Benzodiazepines act as central nervous system depressants, which can lead to tolerance, physical dependence, and withdrawal symptoms. For individuals with a history of substance use disorders, the risk of developing a new dependency on benzodiazepines is particularly concerning.

In treating panic disorder, alternative approaches such as cognitive-behavioral therapy (CBT) and other non-addictive medications, like selective serotonin reuptake inhibitors (SSRIs), may be more appropriate and effective without posing the same risks associated with benzodiazepines. Therefore, it is crucial for healthcare professionals to carefully assess a patient’s history and consider safer treatment options to avoid exacerbating any substance use issues. This aligns with best practices for ensuring patient safety and holistic care in mental health treatment.